I joined Aziz Aboobaker’s lab in February 2015 as a Postdoctoral Research Scientist. During my PhD at Aix Marseille University in France I developed interest in planarians as a model organism for exploring mammalian immunity.
Planarians are best known for their extraordinary regeneration ability conferred by stem cells. Previous research has revealed different types of stem cells and some of genes required for the differentiation of these stem cells into the different lineages that make up differentiated cell types in the planarian body plan.
Here at Planarian-Lab@Oxford I want to understand planarian adult stem cell behaviour during regeneration and how these cells are regulated to respond to injury to allow precise regeneration.
My research will have broad implications for understanding adult stem cell biology in an in vivo model system.
Prasad Abnave, Filippo Conti, Cedric Torre and Eric Ghigo. What RNAi screens in model organisms revealed about microbicidal response in mammals? Frontiers in Cellular and Infection Microbiology. 2015
Prasad Abnave, Giovanna Mottola, Gregory Gimenez, Nicolas Boucherit, Virginie Trouplin, Cedric Torre, Filippo Conti, Amira Ben Amara, Catherine Lepolard, Benjamin Djian, Daniel Hamaoui, Amel Mettouchi, Atul Kumar, Sophie Pagnotta, Stefano Bonatti, Hubert Lepidi, Alessandra Salvetti, Laurent Abi-Rached, Emmanuel Lemichez, Jean-Louis Mege and Eric Ghigo. Screening in planarians identifies MORN2 as a key component in LC3-associated phagocytosis and resistance to bacterial infection. Cell Host & Microbe. 2014; 16(3): 338-350.
Filippo Conti, Prasad Abnave and Eric Ghigo. Unconventional animal models: a booster for new advances in host-pathogen interactions. Frontiers in Cellular and Infection Microbiology. 2014; 4(October):142.
PhD (Human Pathology) at Aix Marseille University, Marseille, France (2012 – 2015)
M.Sc (Biotechnology) at Pune University, Pune, India (2006 – 2008)
Research Fellow at National Chemical Laboratory, Pune, India (2008 – 2011)